CHEM 3750 Chemistry Behind Drugs 3.0 Credits
Covers basic concepts of general and organic chemistry that constitute the foundation of medicinal chemistry. Focuses on applications and problem-solving through active-learning. Offers a comprehensive overview of potential roles for science majors on a medicinal chemistry team. Students will make interdisciplinary connections, while applying nomenclature, stereochemistry and physicochemical properties of functional groups (e.g., water/lipid solubility, electronic effects, acidity/basicity, ionization and salt formation at physiological pH) to predict drug-target and drug-drug interactions, as well as drug metabolic pathways. Using structure-activity relationships and retrosynthetic analysis, students will then design ligands and prodrugs with virtually improved pharmacological action and bioavailability.
Repeat Status: Not repeatable for credit
Prerequisites: CHEM 2422 [Min Grade: D] or CHEM 248 [Min Grade: D] or CHEM 2412 [Min Grade: D] or CHEM 242 [Min Grade: D]
