MCAN 553S Biochemistry of Cancer Therapeutics Discovery 2.0 Credits
This course will provide in-depth coverage of the development of cancer therapeutics, with a special emphasis on the key role of biochemistry at each stage. Biochemical knowledge and skills are required from the early identification of a cancer therapeutic target and hit compounds, through hit-to-lead optimization, to establishing preclinical “absorption, distribution, metabolism, excretion and toxicity” profiles (ADMET) for lead compounds. Discussion of emerging areas in therapeutic design and case studies, both from literature and on-going research programs, will be included to give context to the lecture series.
Repeat Status: Not repeatable for credit
Prerequisites: CMCA 500S [Min Grade: B] and CMCA 501S [Min Grade: B] and CMCA 510S [Min Grade: B]